Which 2023 Anti-anxiety Supplements Are the Most Effective?

Anxiety is your Body’s Natural Response to Stress

Anxiety is a condition that plagues millions all over the world. It comes in many different forms and affects a variety of people. Anxiety is your body’s natural response to stress, and can become a serious chronic condition. It can begin with bouts of panic attacks or as a result of a traumatizing situation from the past. It brings about feelings of apprehension or fear that can become debilitating.

Anti-anxiety supplements effectively ease symptoms of anxiety in many individuals, reducing that stressful rush of nerves in your system and promoting relaxation and a more positive outlook in life. But because anxiety is a generally difficult condition to understand, it’s no surprise that the industry is equally riddled with misconceptions, myths, and false hopes.

Here, we’ve provided you with fast tips and tricks on what to look for when searching for an effective anti-anxiety supplement. By knowing fact from fiction, you will be much better equipped to make a successful purchase.

How Can a Supplement Help with Anxiety?

An integrated approach to managing anxiety symptoms requires a deeper understanding of how supplements fit in and how they should be applied as part of an overall program to reduce symptoms. The classic hurdle for the seriousness of a condition is whether or not it interferes with daily life. Anxiety does. And supplements are an important element in the equation for treatment.

When you find the right anti-anxiety supplement, you’ll find it…


What NOT to Do When Buying an Anti-Anxiety Supplement

DON’T Rely on Amazon Reviews

Some disreputable, fly-by-night companies compensate individuals for positive reviews, regardless of whether they’ve tried the product or not. Risking your health with reviews that are likely false is too dangerous a game to play when you’re choosing an ingestible supplement.

Let’s look at some myths and facts about anxiety and the role of supplements in treating it.

Myths, Misconceptions, and Missed Opportunities

As stated, the business of dealing with anxiety has spawned myriad falsehoods, myths, and misconceptions, in spite of the experience of legions of people who find anti-anxiety supplements life-changing. Let’s sift through some of those mistaken ideas about anxiety as a condition and debunk them.

Anxiety isn’t a “REAL” problem or condition

Nope. Anxiety is a very real and very valid condition that affects millions of people of all types and descriptions. Feelings of anxiety like excessive fear, worry, and nervousness can cause, if left untreated for very long, a degree of impairment that can be increasingly difficult to rein in.

Anxiety claims are just a way to get attention

Really? Anxiety can affect a person physically, mentally, and emotionally, altering body, mind, and behavior. Some symptoms of anxiety can induce problems with one’s breathing, stomach, and sleep. These are often mistaken for attention-seeking tactics when, in fact, these are symptoms should be treated as early as possible, before the condition worsens.

Medication is the only way to treat Anxiety

That’s definitely not the case! In fact, research has shown that those who went through psychotherapy (or “talk therapy”) combined with medication have much better outcomes than those that were just treated with one or the other. Taking anti-anxiety supplements can also ease the symptoms of anxiety and are best taken at the earliest signs of the condition.

Key ingredients in High-Quality Anti-Anxiety supplements


Rhodiola rosea is a perennial flowering plant in the family Crassulaceae. It grows naturally in wild Arctic regions of Europe, Asia, and North America


Ashwagandha is an evergreen shrub that grows in Asia and Africa. … Ashwagandha contains chemicals that might help calm the brain, reduce swelling, lower blood pressure, and alter the immune system.


Lemon balm is a perennial herbaceous plant in the mint family and native to south-central Europe, the Mediterranean Basin, Iran, and Central Asia, but now naturalized elsewhere.


Crataegus, commonly called hawthorn, quickthorn, thornapple, May-tree, whitethorn, or hawberry, is a genus of several hundred species of shrubs and trees in the family Rosaceae


Magnolia grandiflora, commonly known as the southern magnolia or bull bay, is a tree of the family Magnoliaceae native to the southeastern United States, from Virginia to central Florida, and west to East Texas.


Theanine, also known as L-γ-glutamylethylamide and N⁵-ethyl-L-glutamine, is an amino acid analogue of the proteinogenic amino acids L-glutamate and L-glutamine and is found primarily in particular plant and fungal species.


Lutein is a xanthophyll and one of 600 known naturally occurring carotenoids. Lutein is synthesized only by plants, and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots.


Chamomile or camomile, is the common name for several daisy-like plants of the family Asteraceae. Two of the species, Matricaria recutita, and Anthemis nobilis are commonly used to make herbal infusions for beverages.

Facts: Supplements Can Help Overcome Anxiety

Now that we’ve debunked the common misconceptions about anxiety, here is a checklist of three known facts to help you further understand this condition.

You can manage and overcome anxiety

It may seem impossible at first, but managing anxiety is quite possible, especially if you address symptoms at their earliest stages. There are steps you can take to actively work on overcoming this condition. An example is using accessible tools that are proven to be effective in easing the symptoms such as psychotherapy, medication, and anti-anxiety supplements.

There Is No Overnight “Cure” For Anxiety

As mentioned, there are some steps you can take and techniques you can follow to ease the symptoms of anxiety. However, it’s best to note that there is no overnight “cure” for this condition. With time and consistency, however, it is possible to overcome and keep this condition under control, making life livable again.

Anti-Anxiety Supplements Relieve Symptoms Of Anxiety

Anti-anxiety supplements are specially formulated to help maintain your stress levels, elevate your mood, and promote relaxation. They ease symptoms of anxiety, while improving your overall well-being. Taking supplements at the earliest signs of symptoms can greatly reduce the risk of the occurrence of full-blown, debilitating panic attacks and chronic insomnia. The best anti-anxiety supplements are made with only safe, all-natural ingredients, and have no side effects in most people.

After sorting facts from false information, it’s time to seek out which ingredients to look for, and which ones to avoid, in an anti-anxiety supplement. Make sure you only take a supplement that promise premium-quality formulation.

Our Specialized Ranking System

This specialized ranking system follows a unique criteria and comprehensive process in which we measure the value of the products by carefully evaluating the ingredients, safety, efficacy, refund policies, and overall customer satisfaction. These factors, combined with the latest studies and clinical trials, makes it easy to choose the best products available in the market, saving you both time and money.

Unwanted Ingredients In Anti-Anxiety Supplements

Now that we’ve debunked the common misconceptions about anxiety, here is a checklist of three known facts to help you further understand this condition.

Refined Sugar

Consuming excessive amounts of sugar can cause chemical changes in your body. It can makes us feel good, and provides feelings of pleasure. However, these salutatory effects are all temporary. After all, what goes up must come down. When you have a come down from sugar it can result in a sugar hangover.


While it increases speed and efficiency, and temporarily elevates mood, in many people caffeine also triggers the release of the stress hormones cortisol, adrenalin, and noradrenaline. The release of these hormones amplifies any already existing anxiety, elevating nervousness and bring on the jitters.

Food Additives

Dyes and artificial sweeteners are neurotoxins and can leave the neurons in a state of communication breakdown. This disrupts normal nervous system function. When this happens, typically due to an interference in neurotransmission, anxiety and other mood disturbances can occur.

The Top 5 Anti-Anxiety Supplements of 2023

After hours of extensive research, and in consideration of combined ratings and online reviews from customers just like you, we’ve compiled a list of the top five anti-anxiety supplements in the market today.


by Regen Health



Overall Grade


  • Uses safe, all-natural ingredients
  • Reduces anxiety and and stress
  • Reduces risk of panic attacks
  • Balances and elevates mood
  • Promotes relaxation
  • Maintains overall mental health
  • Improves stress and anxiety response
  • No side effects
  • 60-day refund policy


  • Individual results vary

Why we choose it

Coming in at #1 on our list, CALM by Regen Health utilizes a safe, all-natural, and powerful blend of herbal extracts and ingredients to effectively reduce symptoms of anxiety and feelings of stress. It also reduces the risks of panic attacks by promoting relaxation, improving stress and anxiety response, and balancing and elevating mood. CALM is great for mental maintenance and overseeing your overall mental health. It has no known or reported side effects. However, for any reason your are unsatisfied with the product, CALM is backed by the company’s 60-day refund policy. Taking all of these into consideration places the product at #1 on our list.

Mood Boost

by LES Labs



Overall Grade


  • Utilizes an all-natural formula
  • Uses herbal extracts
  • Assists in mood support
  • Promotes positive mood
  • Provides stress and anxiety relief
  • Works fast
  • 60-day refund policy


  • Large capsules
  • May cause side effects

Why we choose it

LES Labs Mood Boost utilizes an all-natural, vegetarian formulation of herbal extracts, as well as L-Tyrosine and L-Theanine that provide quick stress and anxiety relief. The product assists in mood support, boosting general everyday mood, and promoting an overall positive mood. Note, however, that users of LES Labs Mood Boost have reported experiencing a combination of various side effects such as severe mood swings, irritability, increased anxiety, acne, lightheadedness, headaches, palpitations, stomach issues and discomfort, nausea, fatigue, and insomnia. Fortunately, the product is backed by a 60-day refund policy. These place LES Labs Mood Boost at #2.


by Nutratech



Overall Grade


  • Uses all-natural ingredients
  • Unique formulation
  • Maintains a balanced, positive mood
  • Promotes calmness
  • Relieves tension and stress
  • Fast-acting
  • 30-day return policy


  • Unpleasant smell
  • May cause side effects

Why we choose it

Nutratech Alprazium is a fast-acting anti-anxiety supplement that uses a unique formulation of all-natural ingredients to help maintain a balanced, positive mood. The ingredients blend together to promote a calming effect, relieving tension and stress in the process. Despite this, some users of Nutratech Alprazium have reported experiencing multiple side effects such as stomach discomfort, increased anxiety, insomnia, headaches, drowsiness, fatigue, lethargy, heart palpitations, chest tightness, shortness of breath, and chills. Some also mentioned its pungent and unpleasant smell, making it difficult to ingest. The product is backed by the company’s 30-day refund policy. These place Nutratech Alprazium at only #3 on our list.

Anti Anxiety

by Prime Labs



Overall Grade


  • Uses all-natural ingredients
  • Contains B-vitamins
  • Helps reduce anxiety
  • Promotes a calming effect
  • Boosts serotonin production
  • 30-day return policy


  • May cause side effects

Why we choose it

Prime Labs Anti Anxiety uses all-natural ingredients that contain the essential B-vitamins that help reduce anxiety and promote a calming effect. Each capsule is specially formulated with a powerful blend that boosts serotonin production, improving overall daily mood in the process. However, Prime Labs Anti Anxiety my cause side effects such as increased anxiety, irritability, insomnia, lethargy, fatigue, allergic reactions, breakouts, hives, stomach cramps, gas, and head and neck tension. Fortunately, the product is backed by a 30-day refund policy. Taking these into consideration places the product at only #4.

Anxiety Formula

by Optimal Effects



Overall Grade


  • Uses all-natural ingredients
  • Increased levels of calm and positivity
  • Promotes relaxation and focus
  • Reduces symptoms of anxiety
  • Non-drowsy
  • 60-day return policy


  • May cause side effects

Why we choose it

Optimal Effects Anxiety Formula utilizes all-natural ingredients in their anti-stress formula that effectively increases levels of calm and positivity, promoting relaxation without deterring focus. It does not cause drowsiness. Overall, this product should reduce symptoms of anxiety. However, it’s good to note that some users have reported experiencing a combination of numerous side effects such as migraines, blurred vision, high blood pressure, and stomach discomfort. Fortunately, Optimal Effects is backed by a 60-day refund policy. These factors place Optimal Effects Anxiety Formula at only #5 on our list.

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